Precision of hepatitis B virus pregenomic RNA test: a concern on novel biomarker for hepatitis B

نویسندگان

چکیده

No abstract available Sri Lanka Journal of Child Health, 2023: 52(2): 255

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A revised secondary structure model for the 3'-end of hepatitis B virus pregenomic RNA.

The polymerase encoded by human hepatitis B virus, which has reverse transcriptase and RNase H activity, binds to its pregenomic RNA template in a two-step process involving a terminal redundancy. Both first strand and second strand DNA synthesis involve primer translocation and second strand synthesis involves a template jump. Three parts of the genome, including the so-called core promoter, a...

متن کامل

Truncated Hepatitis B virus like nanoparticles: A novel drug delivery platform for cancer therapy

Nowadays, Nano-sized drug delivery systems have been studied extensively for theirpotential in cancer therapy. Various drug nanocarriers are being developed including liposomes, micelles, and Virus like nanoparticles (VLNPs). VLNPs offer many advantages for developing smart drug delivery systems due to their precise and repeated structures and relatively large cargo capacities. Truncated ...

متن کامل

Efficient genome replication of hepatitis B virus using adenovirus vector: a compact pregenomic RNA-expression unit

The complicated replication mechanisms of hepatitis B virus (HBV) have impeded HBV studies and anti-HBV therapy development as well. Herein we report efficient genome replication of HBV applying adenovirus vectors (AdVs) showing high transduction efficiency. Even in primary hepatocytes derived from humanized mice the transduction efficiencies using AdVs were 450-fold higher compared than those ...

متن کامل

The topology of hepatitis B virus pregenomic RNA promotes its replication.

Previous analysis of hepatitis B virus (HBV) indicated base pairing between two cis-acting sequences, the 5' half of the upper stem of epsilon and phi, contributes to the synthesis of minus-strand DNA. Our goal was to identify other cis-acting sequences on the pregenomic RNA (pgRNA) involved in the synthesis of minus-strand DNA. We found that large portions of the pgRNA could be deleted or subs...

متن کامل

A Multistage Group Education for Hepatitis B

Abstract Introduction. Hepatitis B is the most common cause of end stage liver disease in Iran. As a high-cost disease with a relatively high incidence, and the relative lack of community knowledge, it warrants initiation of a public health intervention in Iran. Methods. This was a Before-After educational intervention that analyzed the data obtained from questionnaires filled out by 80 pat...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Sri Lanka Journal of Child Health

سال: 2023

ISSN: ['1391-5452', '2386-110X']

DOI: https://doi.org/10.4038/sljch.v52i2.9609